- May 24 The Fifth Crusade leaves Acre for Egypt.
- Genghis Khan
Great Khan of the Mongol Empire
- Feb 2 Konstantin of Rostov, Prince of Novgorod (b. 1186)
- Jun 25 Simon de Montfort the elder, 5th Earl of Leicester, French crusader dies in the siege of Toulouse
- Jul 6 Eudes III, Duke of Burgundy (b. 1166)
- Aug 31 Al-Malik ab-Adil/Saphadin/Saif al-Din), brother of Saladin, dies
- Dec 30 Richard de Clare, 4th Earl of Hertford, English politician (b. 1162)