- 334 BC The Macedonian army of Alexander the Great defeats Darius III of Persia in the Battle of the Granicus
- 1570 1st atlas 'Theatrum Orbis Terrarum' (Theatre of the World), published by Abraham Ortelius in Antwerp with 70 maps
- 1843 1st wagon train with 700 - 1000 migrants, departs Independence, Missouri for Oregon
- 1939 Adolf Hitler & Benito Mussolini sign "Pact of Steel"
- 1946 First US rocket (WAC Corporal) to reach edge of space fired from White Sands Missile Range New Mexico
Loch Ness Monster is reportably 1st sighted by John Mackay
On May 22, 1933