- Feb 1 Conrad Celtes, German humanist scholar, born in Wipfeld, Germany (d. 1508)
- Mar 2 Adrian VI [Adriaan F Boeyens], Dutch Pope (1522-23) last non-Italian pope for 455 years, born in Utrecht, Holy Roman Empire (d. 1523)
- Mar 6 Jacob Fugger 'Fugger the Rich', German banker and merchant (so rich he financed kings and influenced politics), born in Augsburg, Holy Roman Empire (d. 1525)
- Mar 22 Maximilian I, Holy Roman Emperor (1508-19, established Hapsburg dynasty in Spain), born in Wiener Neustadt, Austria (d. 1519)
- Oct 6 Martin Behaim, German navigator and geographer, born in Nuremberg, Germany (d. 1507)
- Dec 22 Sultan Cem, third son of Sultan Mehmed II and pretender to the Ottoman throne, born in Rumelia, Ottoman Empire (d. 1495)