- Oct 1 Giacomo Barozzi da Vignola, Italian architect, born in Vignola, Italy (d. 1573)
- Oct 19 Viglius ab Aytta Zuichemus [Aytta van Zwichem], Dutch priest
- Oct 29 Fernando Alvarez de Toledo, Spanish noble and diplomat (governor of the Netherlands (1567–1573)), born in Piedrahíta, Ávila, Spain (d. 1582)