- Feb 24 John of Austria, Spanish military leader (Battle of Lepanto), and governor of the Netherlands, born in of Regensburg, Upper Palatinate (now Germany) (d. 1578)
- Mar 1 Rudolph Goclenius, German philosopher (d. 1628)
- May 20 Melchior Bischoff, German composer, born in Pößneck, Germany (d. 1614)
- Jun 28 Cristofano Malvezzi, Italian composer, born in Lucca, Tuscany, Italy (d. 1599)
- Sep 14 Johan van Oldenbarnevelt, Dutch lawyer and statesman, born in Amersfoort, Netherlands (d. 1619)
- Sep 16 Abu al-Faiz ibn Mubarak Faizi, Persian-Dutch East Indies poet, born in Agra, Mughal India (d. 1595)
- Sep 22 Philipp Nikodemus Frischlin, German philologist and poet (d. 1590)
Miguel de Cervantes (1547-1616)
Sep 29 Spanish author (Don Quixote), born in Alcalá de Henares, Habsburg Spain