- Jan 22 Mori Terumoto, Japanese warrior (d. 1625)
- Mar 29 Vitsentzos Kornaros, Greek Renaissance poet, born in Trapezonda, Sitia, Kingdom of Candia (d. 1613 or 1614)
- Apr 30 Louise de Lorraine, Queen consort of France (1575-89), born in Nomeny, Bar, France (d. 1601)
Albert Frederick
May 7 Albert Frederick, Duke of Prussia (1568–1618), born in Konigsberg, Duchy of Prussia (d. 1618)
- May 14 Margaret of Valois, Queen of France, wife of Henry IV (1572-99), daughter of Henry II, born in Château de Saint-Germain-en-Laye, France (d. 1615)
- Jun 5 Bernardino Baldi, Italian mathematician and writer, born in Urbino, Marche, Italy (d. 1617)
- Jun 15 Ernst, archduke of Austria/governor of the Netherlands
- Jul 15 Archduke Ernest of Austria (d. 1595)
- Nov 23 Prospero Alpini, Italian botanist and physician (De Medocoma Aegyptorum)
Henry IV of France
Dec 13 Henry IV, 1st Bourbon King of Navarra (1572-1610) and France (1589-1610), born in Pau, Navarre (d. 1610)
