- Feb 25 Alonso Lobo, Spanish composer (Versa est in luctum), baptized in Osuna, Habsburg Spain (d. 1617)
- Mar 2 Ludovico Spontoni, composer
- Apr 21 Ludovico Carracci, Italian painter, born in Bologna, Italy (d. 1619)
- Aug 1 Edward Kelley, British spirit medium and Renaissance occultist, born in Worcester, England (d. 1597)
- Sep 23 Louise de Coligny, French 4th wife of Willem of Orange
- Dec 4 Heinrich Meibom, German historian and poet, born in Barntrup, Germany (d. 1625)
- Dec 27 Johann Arndt, German Lutheran theologian and author of books on devotional Christianity, born in Edderitz, Anhalt-Köthen, Holy Roman Empire (d. 1621)