- Apr 13 Christina of Holstein-Gottorp, Queen consort of Sweden as the wife of King Charles IX, born in Kiel, Germany (d. 1625)
- Apr 17 Maximilian I, Elector of Bavaria, born in Munich, Germany (d. 1651)
- Apr 26 Marie de' Medici, Queen of France, born in Palazzo Pitti, Florence (d. 1642)