- Jan 4 James Ussher, Irish Archbishop of Armagh (claimed world began Sunday 23 Oct 4004 BC), born in Dublin, Ireland (d. 1656)
- Feb 4 Daniel Selich, German court composer, born in Wittenberg (d. 1626)
- Feb 17 Fausto Poli, Italian Catholic Cardinal. private secretary to Pope Urban, born in Usigni (d. 1653)
- Mar 16 Pieter Corneliszoon Hooft, Dutch historian and writer (d. 1647)
- Apr 24 Vincent de Paul, French Roman Catholic Saint, born in Pouy, Gascony, France (d. 1660)
- May 6 Frans Francken the Younger, Flemish painter, born in Antwerp (d. 1642)
- Jun 18 Thomas Overbury, English poet (A Wife) and essayist, born in Compton Scorpion, Warwickshire, England (d. 1613)
- Jul 2 Johann Staden, German baroque composer, probably born in Nuremberg (d. 1634) baptismal date
- Oct 9 Claude Gaspard Bachet de Meziriac, French mathematician and poet, born in Bourg-en-Bresse, France (d. 1638)
- Oct 21 Domenico Zampieri, Italian painter (d. 1641)
- Dec 9 Emilia Secunda Antwerpiana, 6th and youngest daughter of Willem of Orange, born in Antwerp (d. 1657)