- Apr 11 Pietro Della Valle, Italian composer, born in Rome (d. 1652)
- Apr 17 John Ford, English dramatist ('Tis Pity She's a Whore), born in Ilsington, Devon, England (d. 1639)
- Apr 20 Saint Rose of Lima [Isabel Flores de Olivia], Peruvian saint, a member of the Third Order of Saint Dominic, born in Lima, Peru (d. 1617)