- Jan 13 Maria Anna of Austria, Electress of Bavaria (d. 1665)
- Feb 13 Jean de la Badie, French theologian, founder of Labadists, born in Bourg, Bordeaux, France (d. 1674)
- Mar 1 Johann B Schup, [Schuppius], German poet/historian
- Mar 1 John Pell, English mathematician (d. 1685)
- Mar 4 William Dobson, English portraitist and painter (d. 1646)
- Mar 19 Hasegawa Tohaku, Japanese painter
- Apr 1 Charles de Saint-Évremond, French soldier (d. 1703)
- Apr 22 Alexander VIII, [Pietro Ottoboni], Italian lawyer/Pope (1689-91)
- May 18 Stefano della Bella, Italian printmaker (d. 1664)
- May 24 Giovanni Battista Chinelli, Italian composer, born in Moletolo, Parma, Italy (d. 1677)
- Jun 3 Jacob Neefs, Flemish engraver/publisher, baptised
- Jul 4 Cornelis Evertsen, the Elder, Dutch/Swiss vice-admiral
- Jul 4 Paul Scarron, French playwright (Virgile Travesti)
- Jul 14 Ferdinando II de' Medici, Grand Duke of Tuscany (d. 1670)
- Oct 6 Charles de Sainte-Maure, duc de Montausier, French soldier (d. 1690)
- Oct 19 James Butler, 1st Duke of Ormonde, English statesman and soldier (d. 1688)
- Dec 9 Baldassare Ferri, Italian castrato (d. 1680)
- Dec 12 Basil of Ostrog [Saint Vasilije] Serbian Orthodox bishop, born in Mrkonjići (d. 1671)
- Dec 15 David Teniers II, Flemish courtpainter (Theatrum Pictorium)
- Dec 18 Charles Du Fresne Du Cange, French scholar/philologist