- Jan 6 Christoffer Gabel, Danish statesman, born in Glückstadt, Denmark (d. 1673)
- Jan 30 William Sancroft, 79th Archbishop of Canterbury, born in Fressingfield, Suffolk, England (d. 1693)
- Apr 3 Antimo Liberati, Italian composer, born in Foligno, Italy (d. 1692)
- May 23 Elias Ashmole, English antiquarian and collector (Ashmolean Museum), born in Litchfield (d. 1692)
- Aug 8 Adriaan W "Joris" van Geel, Flemish missionary (Bantu Dictionary)
- Aug 13 Johannes Andreas Quenstedt, German Lutheran theologian, born in Quedlinburg, Germany (d. 1688)
- Nov 19 Eustache Le Sueur, French painter (paintings of religious subjects), born in Paris (d. 1655)