- Mar 10 Constantine Huygens Jr, Dutch poet/painter/cartoonist
- Mar 10 Marcello Malpighi, Italian physician who founded the science of microscopic anatomy, born in Crevalcore, near Bologna, Papal States (d. 1694)
- Mar 17 Daniel van Papenbroeck [Papebrochius], Flemish historian
- Mar 24 Sophie Amalie of Brunswick-Lüneburg, queen of Denmark and Norway (d. 1685)