- Apr 6 Johann Kuhnau, Bohemian organist, choirmaster, and composer (Biblical Sonatas), born in Geising, Bohemia (now Germany) (d. 1722)
- Apr 16 Hans Sloane, Irish physician, naturalist and collector (provided foundation of the British Museum), born in Killyleagh, Ulster, Ireland (d. 1753)
- Apr 19 Sebastián Durón, Spanish composer, born in Brihuega, Guadalajara, Spain (d. 1716)
- Apr 24 Cornelis Dusart, Dutch painter and engraver, born in Haarlem, Netherlands (d. 1704)
- Apr 29 Matthias Henriksen Schacht, Danish scholar and composer, born in Visby, Gotland, Sweden (d. 1700)