- Apr 12 Caffarelli [Gaetano Majorano], Italian castrato soprano, born in Bitonto, Italy (d. 1783)
- Apr 15 Marie-Anne de Cupis de Camargo, French dancer, born in Brussels, Spanish Netherlands (d. 1770)
- Apr 15 William Cullen, Scottish physician and chemist, born in Hamilton, Lanarkshire, Scotland (d. 1790)
- Apr 17 Henry Erskine, 10th Earl of Buchan, British Freemason (d. 1767)
- Apr 25 James Ferguson, Scottish astronomer, born in Banffshire, Scotland (d. 1776)
- Apr 26 Thomas Reid, Scottish philosopher and founder of Scottish School of Common Sense, born in Strachan, Scotland (d. 1796)
- Apr 30 Johann Kaspar Basselet von La Rosée, Bavarian general, born in Arlon, Province of Luxembourg, Belgium (d. 1795)