- Sep 1 Ägid Karl Lickl, Austrian guitar virtuoso, pianist, and composer,born in Vienna (d. 1864)
- Sep 1 Jacobus T Abels, Dutch painter
- Sep 3 Alexander Gurilyov, Russian composer, born in Moscow, Russia (d. 1858)
- Sep 3 Prudence Crandall, American educator and founder of School for "young ladies of colour", born in Hopkinton, Rhode Island (d. 1890)
- Sep 4 Sarah Childress Polk, Wife of the 11th President of the United States, James K. Polk (1845-1849), born in Murfreesboro, Tennessee (d. 1891)
- Sep 19 Maria Anna of Savoy, Empress of Austria and Queen of Hungary and Bohemia, born in Palazzo Colonna, Rome, Papal States (d. 1884)
- Sep 27 Samuel Francis DuPont, American Rear Admiral (Union Navy), born in Bayonne, New Jersey (d. 1865)
- Sep 28 Prosper Mérimée, French author (Carmen), born in Paris (d. 1870)
- Sep 29 Charles-Francois Sturm, French mathematician (Sturm's Theorem), born in Geneva, Switzerland (d. 1855)
- Sep 29 Mercator Cooper, American sea captain (first to visit Japan and Antarctica), born in Southampton, New York (d. 1872)