- Dec 3 Thomas Alfred Davies, American Brevet Major General (Union Army), born in Black Lake, New York (d. 1899)
- Dec 6 Stephen Thomas, American Brigadier General (Union Army), born in Bethel, Vermont (d. 1903)
- Dec 16 Pieter van Bosse, Dutch politician, Liberal Minister of Finance, born in Amsterdam, Netherlands (d. 1879)
- Dec 19 Pierre-Joseph van Beneden, Belgian paleontologist (life cycle of tapeworms), born in Mechelen, Belgium (d. 1894)
- Dec 20 Friedrich Karl Kuhmstedt, German composer, born in Oldisleben, Germany (d. 1858)
Kit Carson (1809-1868)
Dec 24 American frontiersman, Indian fighter and army officer, born in Madison County, Kentucky
William Gladstone (1809-1898)
Dec 29 British statesman and Prime Minister of the United Kingdom (Liberal: 1868-74, 1880-86, 1892-94), born in Liverpool, England