- Oct 2 Anton Emil Titl, Austrian composer, born in Nedvědice (d. 1882)
- Oct 4 Prince Albert of Prussia, Prussian colonel general, born in Königsberg (d. 1872)
- Oct 4 Robert Cumming Schenck, American Major General (Union Army), born in Franklin, Ohio (d. 1890)
- Oct 11 Orson Squire Fowler, American phrenologist and lecturer, born in Cohocton, New York (d. 1887)
- Oct 16 Francesco Schira, composer, born in Island of Malta (d. 1883)
- Oct 22 Federico Ricci, Italian composer, born in Naples, Italy (d. 1877)
- Oct 22 Volney E. Howard, American politician, born in Oxford County, Maine (d. 1889)
- Oct 27 Peter Donders, Dutch Roman Catholic missionary to Suriname, born in Tilburg, Netherlands (d. 1887)