- Sep 4 Juliusz Slowacki, Polish poet (Trip to H Land), born in Kremenets, Russian Empire (d. 1849)
- Sep 5 Manuel Montt Torres, President of Chile (851-61), born in Petorca, Chile (d. 1880)
- Sep 9 William Radford, U.S. Navy rear admiral, born in Fincastle, Virginia (d. 1890)
- Sep 20 Sterling "Old Pap" Price, American lawyer, U.S. Army Brigadier General and politician (11th Governor of Missouri), born in Prince Edward County, Virginia (d. 1867)
- Sep 21 Sophia Hawthorne, American writer, painter and illustrator, born in Salem, Massachusetts (d. 1871)
- Sep 27 Raphael Semmes, American Rear Admiral (Confederate Navy), born in Charles County, Maryland (d. 1877)