- Oct 4 Egbert Benson Brown, American Brigadier General (Union Army), born in Brownsville, New York (d. 1902)
- Oct 6 William Batchelder Bradbury, American composer, born in York, Maine (d. 1868)
- Oct 15 Amiel Weeks Whipple, American Major General (Union Army), born in Greenwich, Massachusetts (d. 1863)
- Oct 16 William Preston, American lawyer, politician and Brigadier General (Confederate Army), born in Louisville, Kentucky (d. 1887)
- Oct 29 Ferdinand II, German prince of the House of Saxe-Coburg and Gotha-Koháry and King of Portugal (1837-53), born in Palais Coburg, Vienna, Austrian Empire (d. 1885)