- Apr 1 Hugo Bezdek, Czech American College Football Hall of Fame coach (University of Oregon, University of Arkansas, Penn State; NFL: Cleveland Browns; MLB: Pittsburgh Pirates), born in Prague, Czech Republic (d. 1952)
- Apr 1 Laurette Taylor [Helen Loretta Cooney], American actress (Peg o' My Heart), born in NYC, New York (d. 1946)
Isoroku Yamamoto (1884-1943)
Apr 4 Japanese World War II Marshall Admiral and Commander-in-Chief of the Japanese fleet who led the attack on Pearl Harbor, born in Nagaoka, Niigata
- Apr 7 Charles Dodd, Welsh theologian (expert on the New Testament), born in Wrexham, Wales (d. 1973)
- Apr 9 Franco Vittadini, Italian composer, born in Pavia, Italy (d. 1948)
- Apr 12 Otto Meyerhof, German psychologist and biochemist (Nobel 1922), born in Hannover, Germany (d. 1951)
- Apr 12 Tenby Davies, Welsh half-mile world champion runner, born in Tenby, Pembrokeshire, Wales (d. 1932)
- Apr 17 Leo Frank, American convict (murder of a 13-year-old employee), born in Cuero, Texas (d. 1915)
- Apr 18 Magda Janssens, Belgian-Dutch actress and acting teacher (Maria Stuart), born in Antwerp, Belgium (d. 1973)
- Apr 20 Princess Beatrice of Saxe-Coburg and Gotha, granddaughter of Queen Victoria, born in Eastwell Park, Kent, England (d. 1966)
- Apr 22 Armas Launis, Finnish composer, born in Hämeenlinna, Finland (d. 1959)
- Apr 25 Arthur Chevrolet, Swiss auto racer and car designer (co-founder Chevrolet Motor Car Company), born in La Chaux-de-Fonds, Switzerland (d. 1946)
- Apr 25 John Henry "Pop" Lloyd, American Baseball HOF shortstop (career batting average: .349 NgLs) and manager (Lincoln Giants, Bacharach Giants), born in Palatka, Florida (d. 1964)
- Apr 27 Louis de Bree [Louis Davids], actor (De man zonder hart, The Cross-Patch, Bluejackets), born in Amsterdam, Noord-Holland, Netherlands (d. 1971)
- Apr 30 Albert Elkus, American composer, born in Sacramento, California (d. 1962)