- Jan 10 UN General Assembly meets for 1st time in London
- Jan 17 United Nations Security Council holds its 1st meeting
- Jan 22 US President Harry Truman sets up the Central Intelligence Agency
- Feb 24 General Juan Perón first elected President of Argentina
- Mar 2 Ho Chi Minh elected President of North Vietnam
- Mar 5 Winston Churchill's "Iron Curtain" speech in Fulton, Missouri, popularizes the term and draws attention to the division of Europe
- Mar 28 Cold War: The United States State Department releases the Acheson-Lilienthal Report, outlining a plan for the international control of nuclear power.
- May 22 First US rocket (WAC Corporal) to reach edge of space fired from White Sands Missile Range New Mexico
- Aug 16 Direct Action Day: Widespread riots erupt in Calcutta between Muslims and Hindus over whether Pakistan should be a separate state, killing over 4,000 and leaving 100,000 homeless
- Sep 30 22 Nazi leaders found guilty of war crimes at Nuremberg
- May 16 "Annie Get Your Gun" musical by Irving Berlin, Dorothy and Herbert Fields opens at Imperial Theater NYC, starring Ethel Merman and featuring "There's no Business Like Show Business"
- Jul 25 At Club 500 in Atlantic City, New Jersey, Dean Martin and Jerry Lewis stage their first show as a comedy team
- Aug 23 "The Big Sleep" directed by Howard Hawks and starring Humphrey Bogart (Philip Marlowe) and Lauren Bacall first premieres
- Dec 20 Christmas classic "It's a Wonderful Life" film premieres in New York, directed by Frank Capra, starring James Stewart, Donna Reed and Lionel Barrymore
World War II: Operation Deadlight ends after scuttling 116 of 156 captured U-boats
On February 11, 1946