- Mar 27 Janus Pannonius, Hungarian poet and translator, dies at 37
- Apr 6 Pieter Bladelin, Belgian land owner (Middelburg castle), dies
- Apr 15 Leon B. Alberti, Italian humanist & architect (Philodoxis), dies at 68
- Apr 25 Leon Battista degli Alberti, scupltor/musician (Dinner Pieces), dies
- Jul 5 Charles of Artois, Count of Eu, French military leader (b. 1394)
- Nov 19 Bessarion, Catholic bishop and famed Greek scholar (revived work of Plato), dies