Andreas Vesalius
Oct 2 Andreas Vesalius [Andries van Wesel], Flemish physician and anatomist (De humani corporis fabrica), dies after being shipwrecked at 49
- Oct 3 Christophorus Fabritius [Christoffel Smit], calvinist vicar, burned
- Oct 4 Pietro P Vergerio, Italian theologist/bishop of Croatia, dies
- Oct 5 Pierre de Manchicourt, Flemish composer, dies at about 54 [birth date uncertain]
- Oct 18 Johannes Acronius Frisius, German physician and mathematician (b. 1520)