- Jan 31 Joost Bürgi, Swiss clockmaker and mathematician (b. 1552)
- Apr 15 George Calvert, English politician & coloniser, dies at 52
- Apr 20 Nicolas Antoine, French Protestant theologian who attempted to convert to Judaism, burned at the stake for heresy aged about 30 in Geneva, Switzerland
- Apr 30 Johann Tserclaes, Count of Tilly, Holy Roman field marshal who commanded the Catholic League's forces in the Thirty Years' War, dies of tetanus after being wounded by a cannonball at 73
Sigismund III Vasa
Apr 30 Sigismund III Vasa, King of Poland and Grand Duke of Lithuania (1587-1632) and King of Sweden (1592-99), dies at 65
- May 25 Adam Tanner, Austrian mathematician and philosopher, dies at 60
- Jun 2 Ernst Casimir, count of Nassau-Dietz/mayor of Friesland, dies at 58
- Jun 22 James Whitelocke, English judge and politician (House of Common 1610-22), dies at 61
- Jul 29 Samuel Ampzing, Dutch poet (Biblical Treasures), dies at 42
- Aug 20 Valentin de Boulogne, French painter, buried at 38
- Aug 25 Thomas Dekker, English dramatist (b. ca. 1572)
- Sep 13 Leopold V, Archduke of Austria, dies at 45
- Sep 17 Susenyos I, Emperor of Ethiopia (1606-1632), dies at around 60
- Oct 12 Kutsuki Mototsuna, Japanese samurai commander (b. 1549)
- Oct 30 Henri de Montmorency, French duke/plotter, beheaded
- Nov 6 Gustavus II Adolphus, King who made Sweden a major power (1611-32), dies at battle of Lützen at 37
- Nov 17 Gottfried Heinrich Graf zu Pappenheim, Bavarian field marshal, dies at 38
- Nov 27 John Eliot, English parliament leader, dies at 40
- Nov 29 Frederick V, Elector Palatine and King of Bohemia, dies at 36
- Dec 8 Philippe van Lansberge, Dutch astronomer, dies at 71