Louis XIII
May 14 Louis XIII, King of France (1610-43), dies at 41

Louis XIII
- Jun 24 John Hampden, English politician, dies of injuries at about 48
- Jul 25 Robert Pierrepont, 1st Earl of Kingston-upon-Hull, English statesman (b. 1584)
- Aug 20 Anne Hutchinson, English Puritan preacher, killed in Native American uprising (b. 1591)
- Sep 15 Richard Boyle, Irish politician, 1st Earl of Cork, dies at 76
- Sep 16 Lucas Franchoys the Elder, Belgian painter, dies at 69
- Sep 20 Lucius Cary, 2nd Viscount Falkland, English politician and writer
- Oct 13 Sweder van Haersolte, mister of Swaluwenborch/diplomat, dies at 61
- Nov 3 Paul Guldin, Swiss astronomer and mathematician (Guldinus theorem), dies at 66
- Nov 3 John Bainbridge, English astronomer (b. 1582)
- Nov 17 Jean-Baptiste Budes, Comte de Guébriant, Marshal of France (b. 1602)
- Nov 29 William Cartwright, English dramatist (b. 1611)
- Nov 29 Claudio Monteverdi, Italian composer and pioneer in development of opera (L'Orfeo,espro della Beata Vergine), dies at 76
- Dec 8 John Pym, English statesman (b. 1583)