- Oct 4 Pierre-Paul Riquet, French engineer
- Oct 8 Elisabeth, Princess of Bohemia and abbess of Herford who corresponded with Descartes, dies at 61
- Oct 13 Daniel Elsevier, Dutch book publisher, dies at 54
- Oct 13 Francois Roberday, French Baroque composer, dies at 56
- Oct 16 Raimondo Montecuccoli, Italian-Austrian general (b. 1608 or 1609)
- Oct 30 Antoinette Bourignon, Flemish mystic (b. 1616)