- Jan 7 Rochus Aerts, Flemish sculptor, dies [or 1739]
- Feb 5 James Stanhope 1st earl of Stanhope, English general, dies at 47
- Feb 16 James Craggs the Younger, English politician, dies at 34
- Feb 24 John Sheffield, 1st Duke of Buckingham and Normanby, English statesman and poet (b. 1648)
- Mar 12 Jan Luyts, Dutch physicist and mathematician, dies at 65
- Mar 16 James Craggs the Elder, English politician (b. 1657)
- Mar 19 Clement XI [Giovanni F Albani], Italian pope (ruled 1700-21), dies at 71
- Apr 14 Michel Chamillart, French statesman (b. 1652)
Mary Read (1685-1721)
Apr 28 English pirate who operated in the Caribbean, dies of a violent fever while in prison and likely still pregnant aged 36
- Jul 8 Elihu Yale, English merchant and philanthropist (benefactor of Yale University), dies at 72
- Jul 18 Jean-Antoine Watteau, French Rococo painter (fêtes galantes), dies at 36
- Jul 25 Geleyn Evertsen, Dutch admiral (commander of Zealand), dies at 66
- Aug 3 Grinling Gibbons, Dutch-born British sculptor and woodcarver, dies at 73
- Aug 13 Jacques Lelong, French bibliographer, dies at 56
- Sep 7 Bernhard Albinus, German-Dutch court-physician (Frederick of Prussia), dies at 68
- Sep 8 Michael Brokoff, Czech sculptor, dies at 35
- Sep 11 Rudolph J. Camerarius, German physician (sexuality plans), dies
- Sep 18 Matthew Prior, English poet and diplomat, dies at 57
- Sep 18 Nathaniel Crew, English influential bishop (Bishop of Oxford and Durham), dies at 88
- Sep 20 Thomas Doggett, British comedy actor (Drury Lane Theatre), dies at approximately 51
- Oct 2 Benott Audran, artist/engraver, dies
- Oct 4 Abraham Alewijn, Dutch poet and playwright (Beslikte Swaantje), dies at 36
- Oct 11 Edward Colston, English merchant, philanthropist and slave trader, dies at 84
- Dec 13 Alexander Selkirk, Scottish sailor and castaway, inspiration for Robinson Crusoe (b. 1676)
- Dec 17 Richard Lumley, 1st Earl of Scarbrough, English statesman (b. 1640)
- Dec 22 Nathaniel Hawes, tortured & executed in England for robbery