- Jan 20 John van Bylevelt, Catholic apostole, dies
- Feb 13 William Wotton, English theologian and scholar, dies at 58
- Mar 22 Francesco Gasparini, Italian baroque composer (Ambleto; Missa Canonica), dies at 59
Isaac Newton
Mar 31 Isaac Newton, English physicist and astronomer (Principia), dies in London at 84
- May 2 Paul Aler, French jesuit and poet (Gradus ad Parnassum), dies at 70
- May 6 Catharine I of Russia [Marta Samuilovna], wife of Peter the Great, dies at about 42
- May 17 Catherine I, Empress of Russia (1725-27), dies at 43
- Jun 8 August Hermann Francke, German Protestant minister (b. 1663)
- Jun 10 George Ludwig, German monarch of Hannover, King of England, dies at 67
- Jun 14 Cornelis Cruys, Norwegian/Dutch admiral, dies at 70
- Jul 23 Simon Harcourt, 1st Viscount Harcourt, Lord Chancellor of Great Britain
- Aug 4 Victor-Maurice, comte de Broglie, French general (b. 1647)
- Aug 6 François Valentijn, Dutch vicar and writer (Old and New East-India), dies at 61
- Aug 9 Johann Philipp Treiber, German composer dies at 52
- Aug 14 William Croft, English composer and organist, dies at 48
- Aug 27 Aert de Gelder, Dutch painter (King David), dies at 81
- Sep 17 Glückel of Hameln, German businesswoman (b. 1647)
- Sep 25 Jacques Abbadie, French theologist, dies at about 73
- Oct 10 Alphonse d'Ève, Flemish Baroque composer, dies at 61
- Nov 10 Alphonse de Tonty, French explorer and American settler (b. 1659)
- Dec 1 Johann Heinrich Buttstett, German composer, dies at 61