- Jan 1 Peregrine Bertie, 2nd Duke of Ancaster and Kesteven, English statesman, dies at 55
- Jan 6 Johann Georg Reinhardt, Austrian organist, composer, and Kappelmeister dies at about 66
Edmond Halley
Jan 14 Edmond Halley, English mathematician and astronomer (Halley's comet), dies at 85 [NS=Jan 25]
- Feb 22 Charles Rivington, English publisher (b. 1688)
- Feb 28 Willem 's-Gravesande, Dutch mathematician and physicist, dies at 53
- Mar 23 Jean-Baptiste Dubos, French writer (b. 1670)
- Apr 2 James Douglas, Scottish physician and anatomist (b. 1675)
- Apr 10 Wilhelmine Amalia of Brunswick-Lüneburg, Holy Roman Empire Empress, dies at 68
- Apr 13 Giovanni Veneziano, Italian composer, dies at 59
- Apr 17 Arvid Horn, Swedish statesman (b. 1664)
- Apr 23 Mihael Omerza, Slovenian composer, dies at 62
- May 11 Francesco Stradivari, Italian violin maker & son of Antonius, dies at 70
- May 13 Ludwig IX, Landgrave of Hesse-Darmstadt (b. 1719)
- May 14 Dominique Marie Valet, French RC/old-catholic bishop, dies at 64
- May 21 Lars Roberg, Swedish physician (b. 1664)
- May 26 Pylyp Orlyk, Ukrainian Zaporozhian Cossack starshina and diplomat, dies at 69
- Jun 8 Omobono Stradivari, Italian violin maker, son of Antonius, dies at 62
- Jun 16 Louise Élisabeth d'Orléans, Queen consort of Spain, dies at 32
- Jun 18 John Aislabie, English politician (Chancellor of the Exchequer), dies at 71
- Jun 28 Jan Josef Ignác Brentner, Bohemian composer, dies at 52
- Jul 1 Bohuslav Matěj Černohorský, Czech monk and composer, dies at 58
- Jul 4 Luigi Guido Grandi, Italian mathematician and monk, dies at 70
- Jul 9 John Oldmixon, English historian (b. 1673)
- Jul 12 Evaristo Felice dall'Abaco, Italian cellist and composer, dies on 67th birthday
- Jul 14 Richard Bentley, English classical scholar who started the 1st written examinations in the West at Cambridge, dies at 80
- Jul 19 John-Baptist Xavery, Flemish sculptor, dies at 45
- Jul 19 William Somervile, English poet (b. 1675)
- Aug 25 José António Carlos de Seixas, Portuguese composer, dies at 38
- Sep 24 Johann Matthias Hase, German scientist (b. 1684)
- Sep 27 Hugh Boulter, Irish Archbishop of Armagh (b. 1672)
- Sep 28 Jean Baptiste Massillon, French churchman, dies at 79
- Nov 12 Friedrich Hoffmann, German physician and chemist (b. 1660)
- Dec 31 Charles III Philip, Elector Palatine (1716-42), dies at 81