- Jan 2 Johann Ludwig Krebs, German musician & composer, dies at 66
- Jan 10 Francesco Antonio Vallotti, Italian organist/composer, dies at 82
William Blackstone
Feb 14 William Blackstone, English jurist (Blackstone's Commentaries), dies at 56

William Blackstone
- Feb 17 Andreas Felix von Oefele, German historian and librarian, dies at 73
- Feb 18 Kristijonas Donelaitis, Lithuanian poet (b. 1714)
- Feb 22 Francesco III d'Este, Duke of Modena & Reggio, dies at 81
- Mar 20 Sir Benjamin Truman - English brewer (b. 1699/1700)
- Mar 26 Charles I, Duke of Brunswick-Lüneburg, dies at 66
- Apr 21 Ferdinand Zellbell the younger, Swedish composer and co-founder of the Royal Swedish Academy of Music, dies at 60
- May 18 Charles Hardy, British governor of Newfoundland, dies at 66
- Jun 3 Thomas Hutchinson, Loyalist politician of the Province of Massachusetts Bay, dies at 68
- Jul 4 Prince Charles Alexander of Lorraine, Imperial Army field marshal, dies at 67
- Jul 14 Charles Batteux, French philosopher, dies at 67
- Aug 3 Etienne B de Condillac, French philosopher (sensualism), dies at 64
- Aug 19 Bernhard Haltenberger, German composer, dies at 32
- Aug 29 Jacques-Germain Soufflot, French architect (b. 1713)
- Sep 1 Reynier de Klerk, governor-general of Dutch-Indies (1777-1800), dies at 69
- Sep 4 John Fielding, English magistrate and social reformer (b. 1721)
William Allen
Sep 6 William Allen, American loyalist, Chief Justice of the Province of Pennsylvania and Mayor of Philadelphia, dies at 76

William Allen
- Sep 8 Enoch Poor, American Continental Army general (b. 1736)
- Oct 2 John Andre, British Army officer of the American Revolutionary War, hanged by Americans (spied with B Arnold) at 30
- Oct 7 Patrick Ferguson, Scottish army officer and rifle inventor (Ferguson flintlock rifle), dies in battle at 36
- Oct 17 William Cookworthy, English chemist, dies at 75
- Nov 14 Jacobus Houbraken, engraver/illustrator, dies at 81
- Nov 17 Bernardo Bellotto, Italian painter (b. 1720)
- Nov 26 James [Denham] Steuart, 4th Baronet, British economist (b. 1712)
- Nov 29 Maria Theresa Hapsburg, Archduchess of Austria, Queen of Hungary and Croatia (1740-1780), dies following illness at 63
- Dec 26 John Fothergill, English physician, dies at 68