- Jan 7 Joseph Lipavsky, Bohemian composer and pianist, dies at 37
- Jan 20 Benjamin Chew, Chief Justice of colonial Pennsylvania, dies at 87
- Jan 28 Andrew Hofer, Tyrolian rebel against French & Bavarians, shot dead
- Feb 20 Andreas Hofer, Tyrolean innkeeper, drover and leader of the Tyrolean Rebellion against the revolutionary Napoleonic invasion during the War of the Fifth Coalition, executed at 42
- Feb 20 Johann Friedrich Kranz, German composer, dies at 57
- Feb 24 Henry Cavendish, British physicist and chemist (discovery of hydrogen), dies at 78
- Feb 26 Johann Ernst Rembt, German organist and composer, dies at 60
- Mar 7 Albertus Henricus Wiese, governor-general of Netherlands Indies, dies at about 48
- Mar 7 Cuthbert Collingwood, 1st Baron Collingwood, British admiral, dies at 61
- Mar 21 Philippe-Joseph van den Berghe graaf Limmighe, Brabants ships, dies
- Apr 7 Pieter L. van de Kasteele, Dutch politician and patriot, dies at 61
- Apr 10 Konrad Back, German monastic composer, dies at 60
- Apr 11 Jakob Zupan, Slovenian composer, dies at 75
- May 2 Henry Jerome de Salis, English churchman, dies at 69
Benjamin Lincoln (1733-1810)
May 9 American military officer (Battles of Saratoga, Charleston and Yorktown during the American Revolutionary War), dies at 77
- May 21 Chevalier d'Éon [Charles-Geneviève-Louis-Auguste-André-Timothée d'Éon de Beaumont], French spy, dies at 81
- Jun 1 Johann Paul Wessely, Czech composer, dies at 47
- Jun 7 Luigi Schiavonetti, Italian engraver (b. 1765)
- Jun 13 Johann Gottfried Seume, German writer (Spaziergang nach Syrakus), dies at 47
- Jun 20 Axel von Fersen the Younger, Swedish Army officer, diplomat and statesman, dies at 54
- Jun 26 Joseph Michel Montgolfier, French inventor (b. 1740)
- Jun 26 Louis d'Affry, French general, military governor of Switzerland and mayor of Freiburg, dies at 67
- Jul 15 Jean-Baptiste Rey, composer, dies at 75
- Jul 19 Luise, queen of Prussia/wife of Frederik Willem III, dies at 34
- Aug 12 Etienne Louis Geoffroy, French pharmacist and entomologist, dies at 84
- Sep 9 Johann Baptiste Hagenauer, Austrian sculptor, dies at 78
- Sep 11 Francis Baring, English merchant and banker (Baring Brothers & Co.), dies at 70
- Sep 20 Wouter Johannes van Troostwijk, Dutch painter, dies at 28
- Sep 28 John Archer, American Congressman who received the 1st medical diploma issued on US continent (1768), dies at 69
- Oct 15 Alfred Moore, American judge (US Supreme Court), dies at 55
- Oct 16 Nachman of Breslov, Ukrainian founder of Breslov Hasidut, dies at 38
- Oct 19 Jean-Georges Noverre, French dancer and choreographer (ballet d'action), dies at 83
- Oct 21 Franz Teyber, Austrian composer, dies at 52
- Nov 1 Georg Anton Kreusser, German composer, dies at 64
- Nov 11 Johan Zoffany, German-born painter patronized by David Garrick and the British Royal family), dies at 77
- Nov 26 Nicolas Etienne Framery, French composer, dies at 65
- Dec 2 Philipp Otto Runge, German Romantic painter, dies at 33
- Dec 19 Johann Heinrich Egli, Swiss violinist and composer, dies at 68