- Jan 5 Major George Johnston, Lieutenant-Governor of New South Wales (b. 1764)
- Jan 17 Zacharius Werner, German playwright, dies at 36
- Jan 21 Cayetano José RodrÃguez, Argentine cleric, journalist and poet (b. 1761)
Edward Jenner
Jan 26 Edward Jenner, English physician, father of immunology, pioneered smallpox vaccinations, dies at 73

Edward Jenner
- Jan 27 Charles Hutton, English mathematician and surveyor, dies at 85