- Jan 5 Major George Johnston, Lieutenant-Governor of New South Wales (b. 1764)
- Jan 17 Zacharius Werner, German playwright, dies at 36
- Jan 21 Cayetano José RodrÃguez, Argentine cleric, journalist and poet (b. 1761)
Edward Jenner
Jan 26 Edward Jenner, English physician, father of (western) immunology, pioneered smallpox vaccinations, dies of a stroke at 73
- Jan 27 Charles Hutton, English mathematician and surveyor, dies at 85