- Jan 13 Ferdinand Ries, German composer dies at 53
- Jan 20 Pierre-Louis Hus-Desforges, French cellist and composer, dies at 64
- Jan 23 Arnold A Buyskes, Dutch vice-admiral/colonial director, dies at 67
- Jan 28 Aleksandr Polezhayev, Russian poet (Sasjka), dies at 33 [OS 16 Jan]
- Jan 30 Osceola, chief of Seminole indians, dies in jail
- Feb 5 Philippe Libon, composer, dies at 62
- Feb 22 Friedrich Johann Eck, German violinist and composer (Concertos pour violon), dies at 70
- Mar 16 Nathaniel Bowditch, American mathematician, astronomer and author (Marine Sextant), dies at 64
- Mar 22 Hendrik Fagel, Dutch/English baron, dies at 73
- Mar 24 Thomas Attwood, English organist and composer, dies at 72
- Apr 3 Francesco Antommarchi, Napoleon's physician on St Helena, dies at 57
- Apr 6 José Bonifácio de Andrada, Brazilian statesman, dies at 74
- Apr 11 Piet [Petrus Lafras] Uys, South African pioneer (Great Pull), murdered at 40
- Apr 17 Johanna Schopenhauer, German writer and mother of Arthur Schopenhauer, dies at 71
- May 12 Jędrzej Śniadecki, Polish writer, physician, chemist (creation of modern Polish terminology in the field of chemistry), dies at 69
Talleyrand
May 17 Charles-Maurice de Talleyrand-Périgord, French statesman, dies at 84
Talleyrand
- May 17 René Caillé, French explorer and the first European to return alive from the town of Timbuktu, dies at 38
- May 23 Jan Willem Janssens, Dutch Governor-General of Cape colony and Dutch-Indies, dies at 75
- May 28 Thomas Busby, English composer, dies at 82
- Jun 25 François-Nicolas-Benoît Haxo, French Army general, dies at 64
- Jul 10 Willem earl van Hogendorp, Dutch colonial governor, dies at about 43
- Jul 17 John Whites, hydraulic engineer, dies at 82
- Jul 19 Frédéric-Nicolas Duvernoy, French horn player and composer, dies at 72
- Jul 28 Bernhard Henrik Crusell, Swedish-Finnish composer, dies at 62
- Jul 29 Jonathan Huntington, composer, dies at 66
- Aug 19 James Geddes, American Engineer (Erie Canal), dies at 75
- Aug 21 Adelbert von Chamisso, French writer (Peter Schlemihl), dies at 57
William Clark
Sep 1 William Clark, American explorer, soldier, Indian agent and territorial governor who led the Lewis and Clark Expedition of 1804-06 and claimed the Pacific Northwest for the United States, dies at 68
William Clark
- Sep 5 Charles Percier, French architect, dies at 74
- Sep 7 Joseph Panny, Austrian violinist and composer, dies at 43
- Sep 8 Pietro Rovelli, composer, dies at 45
- Oct 1 Charles Tennant, Scottish chemist and industrialist, dies at 70
- Oct 3 Black Hawk (chief), Leader of the Sauk Native American tribe (b. 1767)
- Oct 4 Eleanore Sophia Maria Westenholz, German composer, dies at 79
- Oct 15 Letitia Elizabeth Landon, English poet (Heath's Book of Beauty), dies at 36
- Oct 19 Henry Fagel, baron/court clerk of States-General/diplomat, dies at 73
- Nov 24 Karl Ludwig Hellwig, German composer, dies at 65
- Dec 14 Jean-Olivier Chénier, French Canadian physician & Patriote, dies during Battle of Saint-Eustache at 32