- Apr 1 Benjamin Pierce, American politician (b. 1757)
- Apr 11 John Galt, Scottish novelist (Annals of the Parish), dies at 59
- Apr 20 Giuseppe Rossini, father of Italian composer Gioachino Rossini, dies
- Apr 22 Denis Davydov, Russian general & poet, dies at 54
- Apr 23 Jacques Félix Emmanuel Hamelin, French explorer, dies at 70