- Jan 17 Pope Gregory XI moves the Papacy back to Rome from Avignon
- Feb 3 Mass execution of population (between 2,500 and 5,000) of Cesena, Italy, by Breton troops of Giovanni Acuto under the command of Robert, Cardinal of Geneva, acting as the legate of Pope Gregory XI
- May 22 Pope Gregory XI issues five papal bulls to denounce the doctrines of English theologian John Wycliffe
King Richard II
Jun 22 10-year-old Richard of Bordeaux succeeds his grandfather Edward III as Richard II, King of England
- Jun 29 French raid on Rye, England
- Jun 30 Foundation stone laid for Ulm Minster, in Ulm, Germany. Will not be completed until 1890, when it becomes the tallest church in the world.
- Jul 16 Richard II aged 10 crowned King of England at Westminster Abbey, succeeding his grandfather Edward III
First Use of Quarantine
Jul 27 First example of quarantine in Rugusa (now Dubroknik); city council passes law saying newcomers from plague areas must isolation for 30 days (later 40 days, quaranta in Italian)
Gregory I
Gregory XIII
Julius II
Julius III
Leo X
Pius V