Treaty of Interest
Jan 14 Charles V and Francis I sign the Treaty of Madrid, forcing Francis to give up claims to Burgundy, Italy and Flanders

Charles V

Francis I of France
- Feb 8 Heavy storm strikes Dutch coast, many die
- Feb 27 Saxony and Hesse form League of Gotha (league of Protestant princes)
- Mar 15 French Dauphin Francis and his brother Henry exchanged as hostages for their father Francis I, beginning four years of captivity in Spain under Treaty of Madrid
- Mar 17 French King Francis I freed from Spain
- Mar 26 King Francis I returns from Spanish captivity to France
First Battle of Panipat
Apr 21 First Battle of Panipat: Central Asian conqueror Babur defeats Sultan Ibrahim Lodi, establishing the Mughal Empire in India
Learn More- Apr 22 1st slave revolt in the American colonies occurs in South Carolina
- May 2 German evangelical monarchy joins Schmalkaldic League
- May 22 Pope Clemens VII, France, Genoa, Venice, Florence & Milan form Anti-French League of Cognac
- Jun 1 Parliament of Spiers: Lutheran monarchy freed of their belief
Victory in Battle
Aug 29 Battle of Mohács: In a decisive battle the Hungarian Empire is conquered by the Ottoman Empire led by Suleiman the Magnificent

Suleiman the Magnificent