- Apr 12 French King Francois I orders protestants of Vaudois to be killed
Event of Interest
Jul 19 King Henry VIII's flagship Mary Rose sinks at Portsmouth; 73 die
Henry VIII
- Jul 21 The first landing of French troops onto the coast of the Isle of Wight during the French invasion
- Aug 26 Pope Paul III names his son Pierluigi Farnese as Duke of Parma
- Sep 8 English Earl of Hertford leads retaliatory mission against Scotland
- Dec 13 Council of Trent (19th ecumenical council) opened by Pope Paul III