- Jul 10 President Jackson vetoed legislation to re-charter 2nd Bank of US
- Jul 13 Source of Mississippi River discovered by American geographer Henry Schoolcraft
- Jul 14 Opium exempted from federal tariff duty
- Jul 24 Benjamin Bonneville leads the first wagon train across the Rocky Mountains by Wyoming's South Pass
- Jul 25 1st railroad accident in US, Granite Railway, Quincy, Massachusetts, kills 1
- Jul 26 HMS Beagle anchors in Montevideo