- Apr 2 Dave Nourse takes 4 wickets and Reggie Schwarz 3 as South Africa wins the 5th cricket Test in Cape Town to complete a 4-1 series drubbing of England
- Apr 5 St Pius X encyclical "On the Mariavites or Mystic Priests of Poland"
- Apr 5 Mount Vesuvius erupts and devastates towns in the Naples province, killing more than 100 people
1st Animated Film
Apr 6 World's 1st animated cartoon is released, "Humorous Phases of Funny Faces" by J. Stuart Blackton
Historic Event
Apr 14 US President Theodore Roosevelt denounces "muckrakers" in US press, taken from John Bunyan’s Pilgrim’s Progress
San Francisco Earthquake of 1906
Apr 18 San Francisco earthquake and fire kills nearly 4,000 while destroying 75% of the city
- Apr 18 The Los Angeles Times story on the Azusa Street Revival launches Pentecostalism as a worldwide movement
- Apr 19 Belgian naval education ship Comte The Stain de Naeyer sets sail
- Apr 19 SF Earthquake ends killing 452
- Apr 22 Intercalated Games opens in Athens
- Apr 22 New rule puts umpire in sole charge of all game balls
- Apr 26 Motion pictures begin regular showings at the Orpheum Theater in Honolulu, Hawaii