- Sep 1 Two suicide bombings kill 12 people and wound 50 in a NATO base in Afghanistan's Sayed Abad district
- Sep 1 US drone strike kills 5 people in North Waristan, Pakistan
- Sep 1 Islamist rebels seize Douentza, Mali
- Sep 1 Grenade injures 41 festival celebrants in Paquibato, Philippines
- Sep 2 15 people are killed by a car bomb attack at a refugee camp in Sbeineh, Palestine
- Sep 2 A decades-long ban on veiled female news presenters is lifted from State television in Egypt
- Sep 3 New Zealand announces withdrawal of its forces from Afghanistan
- Sep 3 3 people are killed and 19 wounded by a car bombing in Peshawar, Pakistan
- Sep 3 Typhoon Bolaven kills 48 people in North Korea
- Sep 4 25 people are killed at a funeral suicide bombing in Nangarhar, Pakistan
- Sep 4 42 people are killed and 25 injured as a passenger bus falls down a ravine in Morocco
- Sep 4 Pauline Marois becomes the first female premier of Quebec
- Sep 4 Carpet that can help prevent falls among the elderly by warning them of unusual footsteps is developed
- Sep 5 54 people are killed and 50 injured after a firecracker factory explodes in Nadu
- Sep 5 Austerity measure requires Greece to increase its maximum working days to six per week
- Sep 5 25 are killed and 4 wounded after an ammunition store exploded in Afyon, Turkey
- Sep 6 61 illegal immigrants die after a fishing boat capsizes off the coast of Turkey
Presidential Convention
Sep 6 Barack Obama accepts the Democratic nomination for US President
Barack Obama
Music Awards
Sep 6 29th MTV Video Music Awards: Rihanna f/ Calvin Harris, Nicki Minaj & Chris Brown win
- Sep 7 US drone attack kills 8 people in Kismayo, south Somalia
- Sep 7 64 people are killed and 715 injured after a series of earthquakes in south-west China
- Sep 7 Canada closes its Iranian embassy and expels Iranian diplomatic staff out of Canada
- Sep 8 6 people are killed by a Taliban suicide bombing in Kabul, Afghanistan
- Sep 8 8 people are killed after a tractor is hit by a train in Romania
- Sep 9 17 people are killed and at least 40 injured after two car bombs explode in Aleppo, Syria
- Sep 9 100 people are killed and 350 injured after a wave of attacks across Iraq
- Sep 9 Armenia wins the 40th FIDE Chess Olympiad
Tennis Open
Sep 9 US Open Women's Tennis: Serena Williams wins her 4th US title; beats Victoria Azarenka 6-2, 2-6, 7-5
Serena Williams
- Sep 10 16 people are killed by a suicide bombing n Kunduz, Afghanistan
- Sep 10 Teachers in Chicago strike effecting 350,000 students
- Sep 10 10,000 miners demonstrate at Lonmin mines in Marikana, South Africa
- Sep 10 29 people are killed by floods and heavy rain in Vietnam
- Sep 10 A left over bazooka grenade in Cambodia explodes and kills three children
- Sep 10 US Open Men's Tennis: Andy Murray of Scotland wins his first Grand Slam event; beats defending champion Novak Đoković 7-6, 7-5, 2-6, 3-6, 6-2
- Sep 11 50 Al-Shabaab fighters are killed in conflict with the Somali National Army
- Sep 11 The US consulate in Benghazi, Libya, is stormed, looted and burned down, killing five people, including the US ambassador
- Sep 11 The US is warned by Moody's that its AAA credit rating is at risk if lawmakers fail to produce a long-term debt reduction plan
- Sep 11 29 people are killed and 11 injured after a bus runs off a mountain highway in Nepal
- Sep 11 Japan nationalizes three of the disputed Senkaku Islands
- Sep 12 18 soldiers are killed by a rebel car bomb in Syria
- Sep 12 314 people are killed in factory fire in Karachi and Lahore, Pakistan
- Sep 12 Apple unveils its iPhone 5 and iOS 6
- Sep 12 Excavators announce that they may have found the remains of King Richard III of England under a carpark in Leicester
- Sep 13 19 people are killed after a freight elevator crashes from 100 meters in Wuhan, China
- Sep 13 33,000 people are evacuated after Guatemala's Volcano of Fire erupts
Event of Interest
Sep 13 Russian Prime Minister Dmitry Medvedev calls for Russian punk band Pussy Riot to be freed
Dmitry Medvedev
- Sep 13 Dr Mustafa Abushagur is elected as Prime Minister of Libya
- Sep 14 21 people are killed after a ferry sank in Indonesia
- Sep 15 Japan announces that it will phase out nuclear energy by the 2030s
- Sep 16 8 female civilians are killed by a NATO airstrike in Laghman, Afghanistan
- Sep 16 8 police officers are killed by a roadside bombing by Kurdistan Workers' Party militants in Turkey
- Sep 16 14 people are killed and 7 wounded by a roadside bomb Jandol, Turkey
- Sep 16 Anti-Japanese protesters set fire to Panasonic plant in Qingdao, China
- Sep 16 Mayor of Chicago, Rahm Emanuel, seeks a court order to resolve a week long teachers strike
- Sep 16 NHL locks out its players after the expiry of the collective bargaining agreement
- Sep 16 37th Toronto International Film Festival: "Silver Linings Playbook" directed by David O. Russell wins the People's Choice Award
- Sep 17 Panasonic suspends operations at its three factories in China
- Sep 17 China dispatches 1,000 fishing boats to Senkaku Islands
- Sep 17 13 people are killed in a bus accident in Jubail, Saudi Arabia
Event of Interest
Sep 17 Swedish forensic scientists find no conclusive evidence of Wikileaks founder Julian Assange's DNA in a torn condom
Julian Assange
- Sep 17 United States and Japanese government officials agree to put a second missile defence system in Japan
- Sep 18 10 soliders are killed and 70 injured by a missile attack by Kurdish militants in Bingol, Turkey
- Sep 18 26 people are killed in a fire in a Pemex gas facility in Reynosa, Mexico
- Sep 18 The Chicago Teachers Union and Chicago Public Schools reach a deal that ends an 8-day strike.
- Sep 18 World's first mother-to-daughter uterus transplant undertaken at the University of Gothenburg
- Sep 19 9 people are killed and 20 wounded by a car bombing in Peshawar, Afghanistan
- Sep 20 50 people are killed and dozens injured after a gas station is bombed by the Syrian Army in Ain Issa
- Sep 20 14 people are killed in a cafe suicide bombing in Somalia
- Sep 20 AU Optronics fined $500 million for a LCD screen price-fixing
- Sep 21 Japanese Prime Minister, Yoshihiko Noda, wins a leadership ballot
- Sep 22 7 pedestrians are killed by a drunk driver who hit a bus stop at 200km an hour in Moscow
- Sep 23 Iran blocks the use of Google as a search engine
- Sep 23 20 Iranian US Visas are denied, including diplomats and two ministers, ahead of the UN general assembly meeting in New York
- Sep 23 Scientists discover four genetically distinct types of breast cancer
Television Awards
Sep 23 64th Emmy Awards: "Homeland", "Modern Family", Damian Lewis & Claire Danes win
Claire Danes
- Sep 24 Books by Japanese authors or about Japan are suspended by Chinese bookstores
- Sep 25 50 Taiwanese ships clash with the Japan Coast Guard in waters off the Senkaku Islands
- Sep 25 Anouchka van Miltenburg is elected President of the House of Representatives in the Netherlands
- Sep 26 Syrian army massacres 40 civilians in Thiabieh, Damascus
- Sep 26 Greek trade unions call a general strike to protest austerity measures
- Sep 26 Japanese automakers suspend operations in China
- Sep 27 UN publicly releases documents from China and Japan detailing their contesting claims for the Senkoku Islands
- Sep 27 The Mars Curiosity rover discovers what evidence of a fast-moving streambed-in Mars
- Sep 27 The 2004 Japanese discovery of the 133th element has been confirmed
- Sep 28 Aircraft crash kills 16 people in Kathmandu, Nepal
- Sep 28 Nigeria suspends flights to Saudi Arabia after hundreds of Nigerian women travelled without a male escort
- Sep 30 Two opposition Venezuelan politicians are shot dead a week before the presidential election
- Sep 30 Car bomb blasts kill at least 32 people across Iraq
- Sep 30 Melbourne Storm defeat the Canterbury Bulldogs in the 2012 NRL Grand Final
- Sep 30 39th Ryder Cup: Europe wins 14.5-13.5 at the Medinah Country Club in Medinah, Illinois, U.S