- Feb 14 Johann Werner, German mathematician, born in Nuremberg, Germany (d. 1522)
- Feb 29 Paul III, last Renaissance Pope (1534-49)
- Mar 28 Charles I, Duke of Savoy (1482-90), born in Carignano, Piedmont (d. 1490)
- Jun 30 Johann the Steadfast, Elector of Saxony (1525-32), born in Meissen, Electorate of Saxony, Holy Roman Empire (d. 1532)