- Feb 15 Piero di Lorenzo de' Medici [Piero the Unfortunate], Italian ruler of Florence (1492-94), born in Florence, Republic of Florence (d. 1503) [1]
- May 21 Albrecht Dürer, German Renaissance painter and printmaker (Adam and Eve), born in Nuremberg, Germany (d. 1528)
- Jul 15 Eskender, Emperor of Ethiopia (d. 1494)
- Aug 27 George the Bearded, Duke of Saxony (1500-39), born in Meissen, Germany (d. 1539)
- Oct 7 Frederik I, King of Denmark and Norway (1523-33), born in Gottorp, Denmark (d. 1533)
- Oct 15 Konrad Mutian, German humanist, born in Homberg, Hesse, Germany (d. 1526)