- Jan 1 Caspar Cruciger, German church reformer, born in Leipzig (d. 1548)
Pius V (1504-1572)
Jan 17 Italian Pope (1566-72) who excommunicated Elizabeth I of England and arranged the formation of the Holy League (Battle of Lepanto), born in Bosco, Duchy of Milan
- Mar 31 Guru Angad Dev, second Sikh guru, born in Matte Di Sarai, Muktsar, Panjab (d. 1552)
- Jun 2 George van Egmond, Dutch bishop of Utrecht (d. 1560)
- Jul 18 Heinrich Bullinger, Swiss religious reformer, born in Bremgarten, Switzerland (d. 1575)
- Aug 6 Matthew "Nosey" Parker, Archbishop of Canterbury, born in Norwich, England (d. 1575)
- Nov 13 Philip I (the Generous), Landgrave of Hesse and important early protestant ruler, born in Marburg, Landgraviate of Hesse, Holy Roman Empire (d. 1567)
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