- Apr 17 John Ford, English dramatist ('Tis Pity She's a Whore), born in Ilsington, Devon, England (d. 1639)
- Apr 20 Saint Rose of Lima [Isabel Flores de Olivia], Peruvian saint, a member of the Third Order of Saint Dominic, born in Lima, Peru (d. 1617)
- Jul 5 Thomas Hooker, American colonial clergyman (known as "the father of Connecticut"), born in Marefield, Leicestershire, England (d. 1647)
- Jul 7 Thomas Howard, 21st Earl of Arundel, English statesman (d. 1646)
- Aug 8 Adolf, earl of Nassau-Siegen
- Aug 14 William Hutchinson, Rhode Island colonist, born in Alford, Lincolnshire, England (d. 1642)
- Aug 17 Johann V Andreae, German vicar and writer (Christenburg)
- Oct 9 Jan III van Foreest, Dutch lawyer, poet and mayor of Hoorn, born in Alkmaar, Netherlands (d. 1651)
- Oct 9 Leopold V, Archduke of Austria, born in Graz, Austria (d. 1632)
- Dec 6 Niccolò Zucchi, Italian astronomer, born in Parma, Italy (d. 1670)
- Dec 29 Francisco de Moncada, 3rd Marquis of Aitona, Spanish diplomat, soldier, and writer, born in Valencia, Spain (d. 1635)