- Feb 10 Christine Marie of France, regent of Savoy (d. 1663)
- Feb 12 John Winthrop, the Younger, Governor of Connecticut (d. 1676)
- Mar 3 Edmund Waller, English poet (Song: Go, lovely rose) and politician, born in Coleshill, Buckinghamshire, England (d. 1687)
- May 6 Lorenzo Lippi [Perlone Zipoli], Italian poet and painter, born in Florence (d. 1664)
- May 23 Juan Caramuel y Lobkowitz, Spanish writer, born in Madrid, Spain (d. 1682)
- May 25 Charles Garnier, French Jesuit missionary in New France, born in Paris (d. 1649)
- Jun 6 Pierre Corneille, French poet and dramatist (El Cid, Horace), born in Rouen, France (d. 1684)
- Jun 16 Arthur Chichester, 1st Earl of Donegall, Irish soldier (d. 1675)
- Jun 19 James Hamilton, 1st Duke of Hamilton, Scottish statesman, born in Hamilton Palace, Lanarkshire, Scotland (d. 1649)
Rembrandt van Rijn (1606-1669)
Jul 15 Dutch painter (Night Watch), born in Leiden, Netherlands
- Aug 18 Maria Anna of Spain, Holy Roman Empire Empress and Queen of Hungary, born in El Escorial, San Lorenzo de El Escorial, Spain (d. 1646)
- Sep 22 Li Zicheng "Dashing King", Chinese rebel (ousted Ming dynasty and briefly captured Beijing), born in Li Jiqian village, Shaanxi province (d. 1645)
- Oct 14 Joan Maetsuyker, Dutch governor-general of Ceylon (1653-78), born in Amsterdam (d. 1678)
Jeanne Mance (1606-1673)
Nov 12 French-Canadian settler who founded the first hospital in North America (Hôtel-Dieu de Montréal), born in Langres, France
