- Jan 13 Maria Anna of Austria, Electress of Bavaria (d. 1665)
- Feb 13 Jean de la Badie, French theologian, founder of Labadists, born in Bourg, Bordeaux, France (d. 1674)
- Mar 1 Johann Balthasar Schupp, German poet and writer, born in Giessen (d. 1661)
- Mar 1 John Pell, British mathematician and diplomat, born in Southwick, Sussex, England (d. 1685)
- Mar 4 William Dobson, English portraitist and painter (d. 1646)
- Apr 1 Charles de Saint-Évremond, French soldier (d. 1703)
- Apr 22 Alexander VIII [Pietro Ottoboni], Italian Pope (1689-91), born in Venice, Italy (d. 1691)
- May 18 Stefano della Bella, Italian printmaker, born in Florence (d. 1664)
- Jun 3 Jacob Neefs, Flemish engraver and publisher (worked on engravings for major artists including Rubens and van Dyck), born in Antwerp (d. after 1660) baptism date
- Jul 4 Cornelis Evertsen the Elder, Dutch-Swiss vice-admiral, born in Flushing, Netherlands (d. 1666)
- Jul 4 Paul Scarron, French writer (Virgile Travesti), born in Paris (d. 1660)
- Jul 14 Ferdinando II de' Medici, Grand Duke of Tuscany (d. 1670)
- Oct 6 Charles de Sainte-Maure, duc de Montausier, French soldier (d. 1690)
- Oct 19 James Butler, 1st Duke of Ormonde, English statesman and soldier (d. 1688)
- Dec 12 Basil of Ostrog [Saint Vasilije], Serbian Orthodox bishop, born in Mrkonjići (d. 1671)
- Dec 15 David Teniers the Younger, Flemish court painter (Theatrum Pictorium), born in Antwerp (d. 1690)
- Dec 18 Charles du Fresne du Cange, French scholar and philologist, born in Amiens, France (d. 1688)