- Jan 7 Pavao Vitezovic, Croatia, writer and historian, born in Senj, Hapsburg Empire (d. 1713)
- Mar 3 Thomas Otway, English playwright and poet (Venice Preserv'd), born in Trotton, Sussex, England (d. 1685)
- Mar 28 Samuel Sewall, English-American judge and businessman, born in Bishopstoke, Hampshire, England (d. 1730)
- Apr 7 Clement XII [Lorenzo Corsini], Italian Pope (1730-40) who despite ill health and total blindness (1732) unsuccessfully stemmed decline of papal influence, born in Florence (d. 1740)
- Apr 21 Michel Rolle, French mathematician (Rolle's theorem), born in Ambert, Basse-Auvergne (d. 1719)
- May 27 Elisabeth Charlotte "Liselotte", German-French duchess of Orleans, born in Heidelberg Castle, Heidelberg, Electoral Palatinate, Holy Roman Empire (d. 1722)
- Jul 2 Guillielmus "Willem" Kerricx, Flemish sculptor (Rozenkrans), born in Dendermonde, East Flanders (d. 1719)
- Aug 10 Peterus I Scheemaeckers, Flemish sculptor (tomb stones)
- Dec 9 Augustus Quirinus Rivinus, German physician and botanist, born in Leipzig, Germany (d. 1723)
- Dec 25 Archibald Pitcairne, Scottish physician (d. 1713)