- Jan 1 Hong Xiuquan, Chinese rebel (d. 1864)
- Jan 10 Aubrey de Vere, Irish poet & critic (Victorian Observer), born in Toreen, Republic of Ireland (d. 1902)
- Jan 11 James Paget, English surgeon (disease of Paget), born in Great Yarmouth, England (d. 1899)
- Jan 11 Richard Griffith, Brigadier General (Confederate Army), (d. 1862)
- Jan 12 Jones Mitchell Withers, Mjr General (Confederate Army), (d. 1890)
- Jan 17 Ellen Wood, English author (East Lynne, Pomeroy Abbey), born in Worcester, England (d. 1887)
- Jan 24 Abraham van Stolk, Dutch art collector (d. 1896)
- Jan 25 Francis Harrison Pierpont, American lawyer & politician (Union), born in Morgantown, West Virginia (d. 1899)
- Jan 26 Rufus King, American newspaper editor, politician and Brigadier General (Union Army), born in NYC, New York (d. 1876)
- Jan 27 Eugène Viollet-le-Duc, French architect (restored medieval monuments including city of Carcassonne), born in Paris, France (d. 1879)
- Jan 30 Jean-Baptist Capronnier, French-Belgian glass painter, born in Brussels, Belgium (d. 1891)
- Feb 7 Gardner Quincy Colton, American lecturer who was the first to use nitrous oxide as an anesthetic in dentistry, born in Georgia, Vermont (d. 1898)
- Feb 9 Samuel J. Tilden, American politician (Governor of New York 1875-76, Presidential candidate 1876) and philanthropist (NY Public Library), born in New Lebanon, New York (d. 1886)
- Feb 18 Samuel Fenton Cary, U. S. Congressman (d. 1900)
- Feb 25 Taras Shevchenko, Ukrainian national poet and painter, born in Moryntsi, Ukraine (d. 1861) [OS]
- Feb 26 Charles Joseph Sainte-Claire Deville, French geologist (d. 1876)
- Mar 5 Wilhelm von Giesebrecht, German historian (d. 1889)
- Mar 8 Ede Szigligeti [József Szathmáry], Hungarian dramatist, born in Nagyvárad-Olaszi (d. 1878)
- Mar 9 Taras Shevchenko, Ukrainian national poet and painter, born in Moryntsi, Ukraine (d. 1861) [NS]
- Mar 22 Thomas Crawford, American sculptor (Babes in the Wood, Statue of Freedom on dome of US Capitol), born in New York City (d. 1857)
- Mar 28 Galen Clark, Canadian-born American naturalist and conservationist (discovered and helped preserve Mariposa's Grove of giant Sequoia trees), born in Shipton, Canada East (d. 1910) [1]
- Apr 2 Erastus Brigham Bigelow, American inventor of weaving machine, born in West Boylston, Massachusetts (d. 1879)
- Apr 2 Henry L. Benning, American Brigadier General (Confederate Army), born in Columbia County, Georgia (d. 1875)
- Apr 3 Lorenzo Snow, 5th president of the Church of Jesus Christ of Latter-day Saints, born in Mantua, Ohio (d. 1901)
- Apr 4 John Blair Smith Todd, American politician and Brigadier General (Union Army), born in Lexington, Kentucky (d. 1872)
- Apr 15 John Lothrop Motley, American historian and author (The Rise of the Dutch Republic), born in Dorchester, Boston (d. 1877)
- Apr 19 Louis Amédée Achard, French novelist (The Cloak and Dagger), born in Marseille, France (d. 1875)
- Apr 21 Angela Burdett-Coutts, English philanthropist extrordinaire and "the richest heiress in England", born in London (d. 1906)
- Apr 24 Vicente Fidel López, Argentine historian (La Novia del Hereje), born in Buenos Aires, Argentina (d. 1903)
- May 8 Mikhail Bakunin, Russian revolutionary anarchist, born in Pryamukhino, Tver Governorate of the Russian Empire (d. 1876)
- May 14 Charles Beyer, German-British locomotive engineer (d. 1876)
- May 30 Eugène Charles Catalan, French-Belgian mathematician (worked on continued fractions, descriptive geometry, number theory and combinatorics), born in Bruges, Belgium (d. 1894)
- Jun 8 Charles Reade, English novelist (Cloister & Hearth), born in Ipsden, Oxfordshire (d. 1884)
- Jun 8 Thomas Green, American lawyer and soldier (Texas Revolution; Confederate Army General), born in Buckingham County, Virginia (d. 1864)
- Jun 19 Jan Hendrik Weissenbruch, Dutch landscape painter, born in The Hague, Netherlands (d. 1903)
- Jun 22 James Henry Lane, US General during Civil War (Union) and Senator (Kansas), born in Lawrenceburg, Indiana (d. 1866)
Samuel Colt (1814-1862)
Jul 19 American inventor, firearms manufacturer, and industrialist (Colt 6 shot revolver), born in Hartford, Connecticut
- Aug 1 Ivan Gagarin, Russian Jesuit and founding editor of Études, born in Moscow (d. 1882)
- Aug 1 Maxcy Gregg, American Brigadier General (Confederate Army), born in Columbia, South Carolina (d. 1862)
- Aug 8 Esther Morris [Esther Hobart McQuigg], American suffragist, anti-slavery activist, and 1st female justice of the peace in the US, born in Tioga County, New York (d. 1902)
Henri Nestlé (1814-1890)
Aug 10 German-Swiss industrialist (founder of Nestlé), born in Frankfurt, Germany
- Aug 10 John Clifford Pemberton, Lt Gen (Confederate Army), (d. 1881)
- Aug 10 William Lowndes Yancey, MC (Confederacy), (d. 1863)
- Aug 13 Anders Jonas Ångström, Swedish physicist (Spectroscopy), born in Lögdö, Medelpad, Sweden (d. 1874)
- Aug 14 Henry Hayes Lockwood, American Brigadier General (Union Army), born in Kent County, Delaware (d. 1899)
- Aug 23 James Roosevelt Bayley, first Bishop of Newark, New Jersey, and the eighth Archbishop of Baltimore, born in NYC, New York (d. 1877)
- Aug 28 Sheridan Le Fanu, Irish writer (The House by the Churchyard), born in Dublin, Ireland (d. 1873)
- Sep 2 Ernst Curtius, German archaeologist/historian
- Sep 6 George Cartier, Canadian co-PM (1858-62), born in Saint-Antoine-sur-Richelieu, Quebec, Canada (d. 1873)
- Sep 8 Charles-Étienne Brasseur de Bourbourg, French writer and historian, born in Bourbourg, France (d. 1874)
- Sep 13 Nicolas Beets [Hildebrand], Dutch writer (Camera Obscura) and theologian, born in Haarlem, Netherlands (d. 1903)
- Oct 3 Mikhail Lermontov, Russian poet and writer (Demon & other poems), born in Moscow (d. 1841)
- Oct 11 Jean Baptiste Lamy, 1st Archbishop of Santa Fe (1853-85), born in Lempdes, Puy-de-Dôme, France (d. 1888)
- Oct 25 Prince Louis, French Duke of Nemours, born in Palais Royal, Paris (d. 1896)
- Oct 27 Daniel H. Wells, Mormon leader and 3rd Mayor of Salt Lake City, born in Trenton, New York (d. 1891)
- Nov 8 Girolamo de Rada, Albanian poet (Skanderbeku), born in Macchia Albanese, Kingdom of Sicily (d. 1903)
- Nov 13 Joseph Hooker, American Major General (Union Army), born in Hadley, Massachusetts (d. 1879)
- Nov 14 Michael Kelly Lawler, Brevet Major General (Union Army), born in County Kildare, Ireland (d. 1882)
- Nov 15 Pleasant Adam Hackleman, American lawyer, politician and Brigadier General (Union Army), born in Franklin County, Indiana (d. 1862)
- Nov 17 Joseph Finegan, Brigadier General (Confederate Army), (d. 1885)
- Nov 22 Serranus Clinton Hastings, American politician and lawyer (3rd Attorney General of California), born in Watertown, Jefferson County, New York (d. 1893)
- Nov 25 Julius Robert von Mayer, German physician and physicist (first law of thermodynamics), born in Heilbronn, Württemberg (d. 1878)
- Dec 6 Juan Prim, Spanish general and politician (Prime Minister, 1869-70), born in Reus, Catalonia (d. 1870)
Edwin Stanton (1814-1869)
Dec 19 US Secretary of War during most of the American Civil War (1861-65) and US Attorney General (1860-61), born in Steubenville, Ohio