- Jan 10 Muhammad II of Khwarazm, Shah of Khwarazmian Empire (1200-1221), dies on the run from Genghis Khan at 50 or 51
- Aug 6 Saint Dominic, Castilian Catholic priest, founder of the Dominican Order, and patron saint of astronomers, dies at 50
- Oct 4 William III Talvas, Count of Ponthieu (b. 1179)
- Oct 21 Alix of Thouars, Duchess of Brittany (b. 1201)